Prof. Dr. Volker M. Koch, Switzerland

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Biomedical Instrumentation
Fall 2010

 

Overview and Goals

The main goal of this course is to introduce the basics of biomedical instrumentation:

  • Applications: What do we want to diagnose?
  • Physiology: Where are biological signals generated?
  • Sensors: How can we record these signals? 
  • Signals: What properties do these signals have? 
  • Signal processing and analysis: How can we extract useful information from these signals?

This is a compulsory course for all students enrolled in the biomedical engineering master's degree program. Most students will take it during their first semester. Further info: Course description, Vorlesungsverzeichnis

 

News and Messages

  • I have updated my FAQ web page. It now includes a FAQ list on housing and jobs in my group.
  • Sign up for the Swiss IEEE EMBS newsletter if you are interested in biomedical engineering events.

 

Topics, Files

The documents, animations, videos etc. on this page are copyright protected. They can be used for teaching purposes only. Please do not distribute them. Note: To access the following documents, a password is required. If you use Firefox, there is a nice download tool available that you may use to download all PDF documents from a webpage easily. It is called DownThemAll and it is useful beyond this course.

Table of Contents

Day 1
Introduction: exemplary application (cardiac pacemakers), course overview
Files: presentation, solutions, problem set, solutions, "Dreaming On"

Day 2
Origin of biosignals (resting and action potentials, nerve conduction, volume conductor, EEG signals)
Files: presentation, solutions, problem set, solutions

Day 3
Biosignal acquisition (intracellular measurements, biopotential electrodes, half-cell potential of biopotential electrodes, chemical reactions of biopotential electrodes, ECG electrodes, EEG electrodes, active EEG electrodes, EMG electrodes)
Files: presentation, solutions, problem set, solutions

Day 4
Analog biosignal processing (
analog amplifiers, LTspice, analog filters, differentiator)
Files: presentation, solutions, problem set, solutions

Day 5
Digital biosignal processing and analysis (
analog to digital conversion, digital filters, EMG signals, ECG signals, GNU Octave)
Files: presentation, solutions, problem set, solutions

Octave: Octave download, MATLAB primer, An Introduction to Matlab, Octave quick reference, filter.m

Day 6
Digital biosignal processing and analysis programming session (loading ECG signals, displaying signals, filtering signals, finding heartbeats in signals, calculating heartbeat frequency)
Files: no presentation, problem set, ecgSignal.mat, solutions, heartbeats.m

Day 7
Stimulation (defibrillators, evaluation of detection algorithms, functional electrical stimulation, magnetic stimulation, visual stimulation)
Files: presentation, problem set, solutions

Day 8
Electronic implants (hearing implants, retinal implants), ethics
Files: presentation, solutions, problem set, solutions

Day 9
Measurement of the circulatory system (blood pressure)   
Files: presentation, problem set, solutions

Day 10
Measurement of the circulatory system (blood flow, pulse oximetry)
Files: presentation, solutions, problem set, solutions

Day 11
Measurements of the respiratory system (breathing, gas flow)
Files: presentation, solutions, problem set, solutions

Day 12
Measurements of the respiratory system (spirometry, plethysmography)
Files: presentation, solutions (with correction of a mistake I made in class), problem set, solutions

Day 13
Project examples: multi-electrode arrays (Reber), capsule (Lempen), vaginal sensor (Maurer), EIT (Waldmann), energy harvesting (Pfenniger), power measurement (Eichelberger), bruxism (Deschler)

Day 14
Excursion to Medtronic in Tolochenaz

 

Class Location and Time

 

Required Course Book

  • Medical Instrumentation: Application and Design
    John G. Webster, 4th edition, 2009
    ISBN-13: 978-0471676003
    AddAll Price Comparison

 

Further Literature

  • Introduction to Biomedical Engineering
    John Enderle, Susan Blanchard, Joseph Bronzino
    2nd edition, 2005
    ISBN-13: 978-0122386626
     
  • Only for students without knowledge in electrical engineering:
    Schaum's Outline of Electric Circuits
    ISBN-13: 978-0071393072
    Amazon (about 14 € if ordered from Switzerland)
    I recommend to review chapters 1-5 if you do not have a background in electrical engineering.

 

Course Evaluation

 

Exam

  • Written exam, no aids (allowed: pencils, dictionary)
  • Duration: 120 minutes
  • Relevant for the exam are:
    • Problem sets
    • Slides and topics covered in class
  • The course book and the sample solutions can help to understand certain topics better.
  • All exam problems will be in English.
  • Statistics of the exam results can be found here.

 

Excursion to Medtronic in Tolochenaz

 

 

01/2011